| Zdroj: |
ESTHER-1 study group 2017, ' Individualized versus conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial ', Fertility and Sterility, vol. 107, no. 2, pp. 387-396.e4 . https://doi.org/10.1016/j.fertnstert.2016.10.033
FERTILITY AND STERILITY
Nyboe Andersen, A, Nelson, S M, Fauser, B C J M, García-Velasco, J A, Klein, B M, Arce, J-C & ESTHER-1 study group 2017, ' Individualized versus conventional ovarian stimulation for in vitro fertilization : a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial ', Fertility and Sterility, vol. 107, no. 2, pp. 387-396.e4 . https://doi.org/10.1016/j.fertnstert.2016.10.033 |
| Popis: |
Objective:\ud \ud To compare the efficacy and safety of follitropin delta, a new human recombinant FSH with individualized dosing based on serum antimüllerian hormone (AMH) and body weight, with conventional follitropin alfa dosing for ovarian stimulation in women undergoing IVF.\ud \ud Design:\ud \ud Randomized, multicenter, assessor-blinded, noninferiority trial (ESTHER-1).\ud \ud Setting:\ud \ud Reproductive medicine clinics.\ud \ud Patient(s):\ud \ud A total of 1,329 women (aged 18–40 years).\ud \ud Intervention(s):\ud \ud Follitropin delta (AMH |
