Respiratory syncytial virus infection-associated hospitalization in adults: a retrospective cohort study
| Autor: | Rupi Mangat, Kazi Hassan, Cheryl Volling, John Ng, Allison McGeer, Paul Hunter, Ahmed Al-Den, Tony Mazzulli, Karen Green |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Canada medicine.medical_specialty medicine.medical_treatment Respiratory Syncytial Virus Infections Disease Respiratory syncytial virus law.invention Young Adult Medical microbiology Bronchoscopy law Internal medicine Epidemiology medicine Adults Humans Young adult Intensive care medicine Aged Retrospective Studies Aged 80 and over Mechanical ventilation medicine.diagnostic_test business.industry Retrospective cohort study Length of Stay Middle Aged Respiration Artificial Intensive care unit Hospitalization Intensive Care Units Infectious Diseases Female business Research Article |
| Zdroj: | BMC Infectious Diseases |
| ISSN: | 1471-2334 |
| DOI: | 10.1186/s12879-014-0665-2 |
| Popis: | Background Once considered primarily a pediatric concern, respiratory syncytial virus (RSV) infection is gaining recognition as a cause of significant morbidity and mortality in adults. A better understanding of RSV epidemiology and disease in adults is needed to guide patient management and to assess the need for prophylaxis, vaccines, and treatments. Methods We conducted a retrospective cohort study of adults admitted to four hospitals in Toronto, Canada, between September 2012 and June 2013 with RSV identified by a qualitative real-time reverse-transcriptase polymerase chain reaction assay in nasopharyngeal swab or bronchoscopy specimens. Main outcomes were hospital length of stay, need for intensive care unit (ICU) or mechanical ventilation, and all-cause mortality. Results Eighty-six patients were identified as requiring hospitalization for RSV infection (56% female). Median age was 74 (range 19–102) years; 29 (34%) were |
| Databáze: | OpenAIRE |
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