Evaluation of negative-pressure wound therapy for surgical site infections after ileostomy closure in colorectal cancer patients: a prospective multicenter study
| Autor: | Keita Saito, Tetsuhiro Tsuruma, Sasaki K, Masayuki Ishii, Emi Akizuki, Koichi Okuya, Ai Noda, Mitsuhiro Mukaiya, Ichiro Takemasa, Atsushi Hamabe, Tomomi Ueki, Toshihiko Nishidate, Kenji Okita |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Colorectal cancer medicine.medical_treatment Pilot Projects 03 medical and health sciences Ileostomy 0302 clinical medicine Hematoma Negative-pressure wound therapy medicine Clinical endpoint Humans Surgical Wound Infection Prospective Studies Adverse effect Aged Aged 80 and over business.industry Wound Closure Techniques General Medicine Middle Aged medicine.disease Discontinuation Surgery Treatment Outcome 030220 oncology & carcinogenesis Seroma 030211 gastroenterology & hepatology Female business Colorectal Neoplasms Negative-Pressure Wound Therapy |
| Zdroj: | Surgery today. 50(12) |
| ISSN: | 1436-2813 |
| Popis: | Surgical site infection (SSI) occurs at a high rate after ileostomy closure. The effect of preventive negative-pressure wound therapy (NPWT) on SSI development in closed wounds remains controversial. We conducted a prospective multicenter study to evaluate the usefulness of preventive NPWT for SSI after ileostomy closure. From January 2018 to November 2018, 50 patients who underwent closure of ileostomy created after surgery for colorectal cancer participated in this study. An NPWT device was applied to each wound immediately after surgery and then treatment was continued for 3 days. The primary endpoint was 30-day SSI, and the secondary endpoints were the incidence of seroma, hematoma, and adverse events related to NPWT. No patients developed SSI, seroma, or hematoma. Adverse events that may have been causally linked with NPWT were contact dermatitis in two patients and wound pain in one patient, and there were no cases of discontinuation or decompression of NPWT. The use of NPWT following ileostomy closure may be useful for reducing the development of SSI in colorectal cancer patients. This is a prospective multicenter pilot study and we are planning a comparative study based on these successful results. Registration number: UMIN000032053 ( https://www.umin.ac.jp/ ). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink