Syn stereochemistry of cyclic ether formation in 1,8-cineole biosynthesis catalyzed by recombinant synthase from Salvia officinalis

Autor:	Robert M. Coates, Marek Urbansky, Rodney Croteau, Mitchell L. Wise, Gregory L. Helms
Rok vydání:	2002
Předmět:	Stereochemistry Monoterpene Biochemistry Catalysis Enzyme catalysis chemistry.chemical_compound Colloid and Surface Chemistry food Biosynthesis medicine Carbon-Carbon Lyases Salvia officinalis Nuclear Magnetic Resonance Biomolecular Plant Proteins Eucalyptol Bicyclic molecule ATP synthase biology Terpenes Stereoisomerism General Chemistry Cyclohexanols food.food Recombinant Proteins Mechanism of action chemistry biology.protein Monoterpenes Stereoselectivity medicine.symptom
Zdroj:	Journal of the American Chemical Society. 124(29)
ISSN:	0002-7863
Popis:	Regiospecifically labeled geranyl diphosphates ((2E,6E)-[1,1,8,8,8-(2)H(5)]- and (2E,6Z)-[1,1,9,9,9-(2)H(5)]-GDP) and D(2)O incorporation, in concert with NMR spectrometry, were employed to demonstrate a unique intramolecular syn-facial protonation-cyclization mechanism of action of 1,8-cineole synthase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5b3fdb8be01db4ca615d7f4ff5fa83 https://pubmed.ncbi.nlm.nih.gov/12121093 Zobrazit plný text záznamu