IgG4 Staining in Thyroid Eye Disease
| Autor: | Saul Rajak, Irwin Kashani, Nicholas H Andrew, Daniel Kearney, Dinesh Selva |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pathology
medicine.medical_specialty Triamcinolone acetonide Eye disease Plasma Cells Inflammation 03 medical and health sciences 0302 clinical medicine parasitic diseases Biopsy medicine Humans In patient Aged Staining and Labeling integumentary system medicine.diagnostic_test business.industry fungi Thyroid General Medicine Levator Palpebrae Superioris medicine.disease eye diseases Staining Graves Ophthalmopathy Ophthalmology medicine.anatomical_structure Oculomotor Muscles Immunoglobulin G 030220 oncology & carcinogenesis 030221 ophthalmology & optometry Female Surgery medicine.symptom business medicine.drug |
| Zdroj: | Ophthalmic Plastic & Reconstructive Surgery. 33:S183-S185 |
| ISSN: | 0740-9303 |
| DOI: | 10.1097/iop.0000000000000556 |
| Popis: | IgG4-related ophthalmic disease is increasingly widely recognized. Moreover, IgG4 staining can occur in other inflammatory diseases. The authors report a case of IgG4 staining of an enlarged, inflamed levator palpebrae superioris in a patient with a past history of thyroid eye disease. A 78-year-old woman with quiescent hyperthyroidism had clinical and radiological evidence of levator palpebrae superioris inflammation without superior rectus involvement. A biopsy was consistent with IgG4-related ophthalmic disease. There was a marked but incomplete response to an orbital injection of triamcinolone. The authors discuss the association between thyroid eye disease and IgG4 staining and the diagnostic issues that arise when IgG4-related ophthalmic disease criteria are fulfilled in patients with other orbital inflammatory conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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