Fibrin sealants in orthopaedic surgery: practical experiences derived from use of QUIXIL® in total knee arthroplasty
| Autor: | Andreas Suckel, Beate Kunze, Katrin Fiedler, Ingmar Ipach, Torsten Kluba |
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| Rok vydání: | 2011 |
| Předmět: |
musculoskeletal diseases
Male medicine.medical_specialty Fibrin sealants business.industry Total knee arthroplasty General Medicine Perioperative Fibrin Tissue Adhesive Postoperative Blood Loss Surgery Blood loss Orthopedic surgery Medicine Humans Orthopedics and Sports Medicine Female Single-Blind Method Prospective Studies business Arthroplasty Replacement Knee Aged |
| Zdroj: | Archives of orthopaedic and trauma surgery. 132(8) |
| ISSN: | 1434-3916 |
| Popis: | Total knee arthroplasty is associated with a significant postoperative blood loss even without any form of perioperative anticoagulation.The potential role of QUIXIL(®), a fibrin sealant used in orthopaedic surgery to control blood loss and avoid blood transfusions in patients undergoing total knee arthroplasty was evaluated in a prospective randomized trial with twenty-four patients diagnosed with primary osteoarthritis of the knee.Results showed that application of 2 ml QUIXIL(®) adds costs to treatment without reducing the number of transfused red blood cell counts and postoperative haemoglobin loss. However, significant lower levels of postoperative fluid loss (P = 0.026) was detected in QUIXIL(®) treated patients.Regarding cost effectiveness and benefit no indication for the use of 2 ml QUIXIL(®) fibrin sealant in standard knee arthroplasty could be proofed statistically. |
| Databáze: | OpenAIRE |
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