Timing of Last Preoperative Dose of Infliximab Does Not Increase Postoperative Complications in Inflammatory Bowel Disease Patients

Autor: Jill K. J. Gaidos, John F. Kuemmerle, Le Kang, Anas Alsaleh
Rok vydání: 2016
Předmět:
Male
Time Factors
Physiology
Anastomotic Leak
Inflammatory bowel disease
Postoperative Complications
0302 clinical medicine
Transplant surgery
Crohn Disease
Risk Factors
Child
skin and connective tissue diseases
Digestive System Surgical Procedures
Crohn's disease
Gastroenterology
Venous Thromboembolism
Middle Aged
Ulcerative colitis
030220 oncology & carcinogenesis
Female
030211 gastroenterology & hepatology
medicine.drug
Adult
Reoperation
musculoskeletal diseases
medicine.medical_specialty
Abdominal Abscess
Adolescent
Article
Young Adult
03 medical and health sciences
Ileus
Gastrointestinal Agents
Internal medicine
Preoperative Care
medicine
Humans
Surgical Wound Infection
In patient
Retrospective Studies
business.industry
Hepatology
Inflammatory Bowel Diseases
medicine.disease
Infliximab
digestive system diseases
Surgery
stomatognathic diseases
Colitis
Ulcerative
business
Intestinal Obstruction
Zdroj: Digestive Diseases and Sciences. 61:2602-2607
ISSN: 1573-2568
0163-2116
Popis: The association between preoperative use of infliximab and postoperative complications in patients with inflammatory bowel disease (IBD) is a subject of continued debate. Results from studies examining an association between the timing of last preoperative dose of infliximab and postoperative complications remain inconsistent.To assess whether timing of last dose of infliximab prior to surgery affects the rate of postoperative complications in patients with Crohn's disease or ulcerative colitis.Retrospective chart review of IBD patients who have undergone surgery while receiving therapy with infliximab was conducted. Forty-seven patients were included in the analysis.No significant association was found between timing of infliximab and the rate of postoperative complications. Age, gender, disease type, steroid use, preoperative status, surgery type, or surgeon type was not associated with increased rate of postoperative complications.Timing of last dose of infliximab does not affect the rate of postoperative complications in patients with Crohn's disease or ulcerative colitis.
Databáze: OpenAIRE
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