Plasma norepinephrine after a standardized test meal in acute and remitted patients with anorexia nervosa and in healthy controls
| Autor: | Manfred M. Fichter, Michael Kellner, Elisabeth Philipp, Karl M. Pirke, Reinhold G. Laessle, Jfigen Christian Krieg |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
medicine.medical_specialty Sympathetic nervous system Anorexia Nervosa Personality Inventory Norepinephrine (medication) Norepinephrine Orthostatic vital signs Internal medicine Blood plasma medicine Humans Biological Psychiatry Body Weight Hypothermia Prognosis Hospitalization Endocrinology medicine.anatomical_structure Blood pressure Anorexia nervosa (differential diagnoses) Anorectic Female medicine.symptom Arousal Energy Intake Psychology medicine.drug |
| Zdroj: | Biological Psychiatry. 31:1074-1077 |
| ISSN: | 0006-3223 |
| DOI: | 10.1016/0006-3223(92)90102-6 |
| Popis: | The reduced activity of the peripheral sympathetic nervous system of anorectic patients is reflected in low blood pressure, low pulse rate, hypothermia, etc. Norepinephrine and its membolites in plasma, urine, and cerebrospinal fluid show low concentrations (for ~eview see Pirke 1990). The reduced activity of the sympathetic nervous system can be stimulated by an orthostatic challenge (Kaye et al 1985; Heufelder et al 1985) and by exercise (Nudel et al 1984; Pirke et al 1989) although to a lesser extent than in controls. Kaye et al (1985) found decreased norepinephrine levels in plasma before and after an orthostatic challenge in long-term ( 6 72 months) weight recovered anorectic patients. These former patients had eitl~er intermediate or good outcome. Norepinephrine plays a role in the regulation of hunger and satiety (Leibowitz 1984) in many neuroendocrine and neurophysiological regulatory systems and it is correlated with mood disturbances in anorexia nervosa (Halmi et al |
| Databáze: | OpenAIRE |
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