A peculiar case report of extraovarian Brenner tumor arising in the omentum
| Autor: | Hyun Jeong Kang, Ahrong Kim, So Jeong Lee, Young Geum Kim, Dong Hoon Shin, Chang Hun Lee, Chung Su Hwang, Do Youn Park |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Adult
0301 basic medicine Pathology medicine.medical_specialty Stromal cell Brenner Tumor lcsh:Surgery CD34 Case Report Ovary lcsh:RC254-282 03 medical and health sciences 0302 clinical medicine medicine Humans Stromal tumor Ovarian Neoplasms Extraovarian business.industry lcsh:RD1-811 Cystic Change lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Prognosis 030104 developmental biology medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Abdomen Immunohistochemistry Female Surgery Stromal Cells business Omentum |
| Zdroj: | World Journal of Surgical Oncology World Journal of Surgical Oncology, Vol 15, Iss 1, Pp 1-5 (2017) |
| ISSN: | 1477-7819 |
| DOI: | 10.1186/s12957-017-1135-2 |
| Popis: | Background Brenner tumors almost always develop in the ovary. Exceptionally, extraovarian Brenner tumors have been reported in the lower abdomen or pelvic organs. Here, we introduce a peculiar case of an extraovarian Brenner tumor arising in the omentum. Case presentation A 43-year-old woman presented with a palpable abdominal mass. Computed tomography (CT) scan revealed a 9.0-cm solid mass in the omentum. The tumor was not associated with pelvic structures, including the ovaries. It was excised under the clinical impression of an extragastrointestinal stromal tumor or neurogenic tumor. Grossly, the mass was a well-circumscribed solid tumor, with yellow-tan cut surface and minute cystic spaces. Microscopically, the tumor showed well-defined epithelial nests with variable cystic changes embedded in an abundant fibrous stroma. The cells within the nests were reminiscent of benign urothelial cells in that they had oval, frequently grooved nuclei. The epithelial cells focally showed a gradual transition into the surrounding stromal cells with short spindled features. The urothelium-like cells were positive for pancytokeratin, WT-1, p63, CK7, uroplakin-III, and GATA-3 but were negative for CD34, CD10, CK20, c-KIT, DOG-1, PAX-8, and calretinin. Morphological and immunohistochemical features of the tumor were the same as an ovarian Brenner tumor, and so it was diagnosed as an extraovarian Brenner tumor. Conclusions Although the location of the tumor was very unusual, we could diagnose the tumor as an extraovarian Brenner tumor on the basis of the histologic and immunohistochemical findings. This is the first case of extraovarian Brenner tumor arising in the omentum near the stomach ever reported in the English literature. |
| Databáze: | OpenAIRE |
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