Successful treatment of facial localized discoid lupus erythematosus with intralesional betamethasone: A report of three cases
| Autor: | Huan‐Yan Liu, Jingyao Liang, Xiao-Dong Liang, Rui‐xian Ye, Qi‐Ying Xiong, Xibao Zhang, Liang‐Jiao Dong, Jie Deng |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Discoid lupus erythematosus Administration Topical Dermatology Autoimmune skin disease Administration Cutaneous Betamethasone 030207 dermatology & venereal diseases 03 medical and health sciences Cicatrix 0302 clinical medicine Atrophy Lupus Erythematosus Discoid Intralesional injections Refractory Medicine Humans business.industry General Medicine medicine.disease Male patient 030220 oncology & carcinogenesis business Skin lesion medicine.drug |
| Zdroj: | Dermatologic therapyREFERENCES. 33(3) |
| ISSN: | 1529-8019 |
| Popis: | Discoid lupus erythematosus (DLE) is a chronic autoimmune skin disease that usually causes disfiguring scarring, dyspigmentation, and atrophy. Despite a range of available topical and systemic therapies, the treatment of DLE remains a therapeutic challenge, especially in some refractory cases. Here, we reported three male patients with long-term chronic lesions of unilateral facial localized DLE, who failed to have their disease controlled with many previous topical/systemic treatments, showed rapid and well response to intralesional injections of betamethasone (2 mg/mL, 0.2 mL/site) monotherapy once every 2 weeks for two, two, and four times of treatment, respectively. Intralesional betamethasone may provide a safe and effective alternative in the management of refractory localized DLE skin lesions. |
| Databáze: | OpenAIRE |
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