Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis
Autor: | Korosh Ashrafi-Dehkordi, Zohreh Alizadeh, Reza Aramideh Khouy, Mehdi Banitalebi-Dehkordi, Samira Sanami, Hamed Nosrati, Mohammad Khodaei, Ali Nosrati |
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Rok vydání: | 2021 |
Předmět: |
Vascular Endothelial Growth Factor A
Chronic wound Scaffold lcsh:Medical technology Angiogenesis lcsh:Biotechnology Biomedical Engineering Wound healing Pharmaceutical Science Medicine (miscellaneous) Bioengineering Review Applied Microbiology and Biotechnology Nanocomposites Tissue engineering Skin tissue lcsh:TP248.13-248.65 Animals Humans Medicine Skin tissue engineering Skin Tissue Engineering Tissue Scaffolds business.industry Regeneration (biology) Nanobiotechnology Key factors lcsh:R855-855.5 Quality of Life Blood Vessels Molecular Medicine Angiogenesis Inducing Agents medicine.symptom business Angiopoietins Biomedical engineering |
Zdroj: | Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-21 (2021) Journal of Nanobiotechnology |
ISSN: | 1477-3155 |
DOI: | 10.1186/s12951-020-00755-7 |
Popis: | Skin is the body’s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life. Tissue engineering aims to improve the quality of damaged tissue regeneration. One of the most effective treatments for skin tissue regeneration is to improve angiogenesis during the healing period. Over the last decade, there has been an impressive growth of new potential applications for nanobiomaterials in tissue engineering. Various approaches have been developed to improve the rate and quality of the healing process using angiogenic nanomaterials. In this review, we focused on molecular mechanisms and key factors in angiogenesis, the role of nanobiomaterials in angiogenesis, and scaffold-based tissue engineering approaches for accelerated wound healing based on improved angiogenesis. |
Databáze: | OpenAIRE |
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