A clinical study on the usefulness of autologous plasma filler in the treatment of nasolabial fold wrinkles

Autor:	Han-Saem Kim, Won-Serk Kim, Jae-Hui Nam, Ga-Young Lee, Joon Hong Min, Young-Jun Choi
Rok vydání:	2017
Předmět:	Adult medicine.medical_specialty Nasolabial Fold food.ingredient Esthetics Dermatology Clinical study Plasma 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Patient satisfaction food Autologous plasma Dermal Fillers medicine Humans Autografts Adverse effect Wrinkle business.industry Middle Aged Nasolabial fold Skin Aging Surgery Treatment Outcome medicine.anatomical_structure Patient Satisfaction 030220 oncology & carcinogenesis Assessment methods Rhytidoplasty Female medicine.symptom business Filler (animal food)
Zdroj:	Journal of Cosmetic and Laser Therapy. 19:174-180
ISSN:	1476-4180 1476-4172
DOI:	10.1080/14764172.2016.1248443
Popis:	Recently, the efficacy of autologous plasma filler for the reduction of facial wrinkles has been demonstrated.The aim of our study is to validate the efficacy and safety of autologous plasma filler in treating nasolabial fold wrinkles.Twenty Korean patients with moderate-to-severe nasolabial fold wrinkles were enrolled. The patients were treated with one session of autologous plasma filler. The wrinkle improvement effects were evaluated at 1-week, 4-week, 8-week, and 12-week after the treatment. Three assessment methods were applied. First, two independent dermatologists assessed cosmetic results using a 5-point wrinkle assessment scale. Second, global aesthetic improvement score was used for assessment of the final cosmetic results. Third, patient satisfaction was surveyed. Also, the adverse effects associated to treatment were observed.Mean age of the patients was 44.5 years. The average 5-point wrinkle assessment scale score was significantly improved at 1, 4, 8, and 12 weeks after treatment, comparing to before treatment (p0.01). The patients' average global aesthetic improvement score also indicated better cosmetic outcomes.The clinical improvement with sufficient patients' satisfaction and no significant adverse events demonstrated that novel autologous plasma filler could be considered as efficient and safety treatment option for nasolabial fold wrinkles.
Databáze:	OpenAIRE
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