Parosteal Osteosarcoma: A Benign-Looking Tumour, Amenable to a Variety of Surgical Reconstruction
| Autor: | Samuel Maruanaya, Toto Suryo Efar, Yogi Prabowo, Achmad Fauzi Kamal, Evelina Kodrat, Marcel Prasetyo |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male musculoskeletal diseases medicine.medical_specialty Article Subject Adolescent Parosteal osteosarcoma Tertiary referral hospital Extracorporeal Young Adult 03 medical and health sciences Rare Diseases 0302 clinical medicine Humans Medicine Femur RC254-282 Fixation (histology) business.industry Femoral Neoplasms Neoplasms. Tumors. Oncology. Including cancer and carcinogens Chemoradiotherapy Adjuvant 030206 dentistry Middle Aged Plastic Surgery Procedures Osteosarcoma Juxtacortical medicine.disease Oncology Indonesia 030220 oncology & carcinogenesis Osteosarcoma Female Surgery Radiology business Chemoradiotherapy Research Article Follow-Up Studies Rare disease |
| Zdroj: | International Journal of Surgical Oncology International Journal of Surgical Oncology, Vol 2020 (2020) |
| ISSN: | 2090-1410 2090-1402 |
| Popis: | Osteosarcoma arising from cortical surface is classified into parosteal, periosteal and high-grade surface osteosarcoma. Along the spectrum, parosteal osteosarcoma occupies the well-differentiated end. It is a relatively rare disease entity, comprised only 4% of all osteosarcomas and barely reported in the literature. The objective of this study is to describe cases of parosteal osteosarcoma as well as a variety of treatment options amenable to such entity. Six cases of parosteal osteosarcoma were identified based on histopathological reports in a tertiary referral hospital in Jakarta, Indonesia between January 2001 and December 2019. The mean age was 29.8 years old; four of them (66.7%) were male. Distal end of femur was the most commonly involved bone (five cases, 83.3%). The patients were treated with wide excision followed by several different reconstruction methods: replacement with endoprosthesis, extracorporeal irradiation, knee arthrodesis, or prophylactic fixation. One of our patients presented with dedifferentiated component, and therefore was treated by limb ablation. While two cases died of pulmonary metastasis, other patients reported fair to excellent functional outcome. |
| Databáze: | OpenAIRE |
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