Procalcitonin and intestinal ischemia: A review of the literature
| Autor: | Antoine Galmiche, Cyril Cosse, JM Regimbeau, Said Kamel, Charles Sabbagh |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Calcitonin
medicine.medical_specialty Calcitonin Gene-Related Peptide Ischemia Diagnostic accuracy Review Diagnostic tools Gastroenterology Procalcitonin Predictive Value of Tests Risk Factors Internal medicine Daily practice parasitic diseases medicine Animals Humans Intestinal Mucosa Protein Precursors Intensive care medicine Receiver operating characteristic business.industry Intestinal ischemia General Medicine Prognosis bacterial infections and mycoses medicine.disease Predictive value Intestines Area Under Curve business Biomarkers hormones hormone substitutes and hormone antagonists Signal Transduction |
| Zdroj: | World Journal of Gastroenterology. 20:17773-17778 |
| ISSN: | 1007-9327 |
| DOI: | 10.3748/wjg.v20.i47.17773 |
| Popis: | Intestinal ischemia is common after emergency gastrointestinal or cardiovascular surgery. At present, there are no diagnostic tools for the early diagnosis of intestinal ischemia. In the last decade, procalcitonin (PCT) has been suggested as a marker of this condition. Here, we review the use of PCT as a diagnostic tool for intestinal ischemia. Two reviewers independently searched the PubMed and EMBASE databases for articles on intestinal ischemia and PCT. They then considered (1) the criteria applicable to preclinical and clinical data; and (2) PCT’s predictive value in the diagnosis of intestinal ischemia. Article quality was rated according to the STAndards for Reporting of Diagnostic accuracy. Between 1993 and 2014, seven studies (including two preclinical studies and five clinical studies) dealt with the use of PCT to diagnose intestinal ischemia. Procalcitonin’s sensitivity, specificity, positive predictive value and negative predictive value ranged between 72% and 100%; 68% and 91%; 27% and 90% and 81% and 100%, respectively. The area under the receiver operating characteristic curve ranged from 0.77 to 0.92. In view of the preclinical and clinical data, we consider that PCT can be used in daily practice as a tool for diagnosing intestinal ischemia. |
| Databáze: | OpenAIRE |
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