Reduction of excessive haematocrit levels in patients with polycythaemia due to hypoxic lung disesae by phenylhydrazine hydrochloride and pyrimethamine
| Autor: | C. D. R. Pengelly |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Adult
Lung Diseases Male medicine.medical_specialty Polycythaemia Polycythemia Hematocrit Gastroenterology hemic and lymphatic diseases Phenylhydrazine hydrochloride Internal medicine medicine Humans In patient Platelet Hypoxia Aged Lung medicine.diagnostic_test business.industry Articles General Medicine Middle Aged medicine.disease Phenylhydrazines Surgery Pyrimethamine medicine.anatomical_structure Lung disease Female business medicine.drug |
| Zdroj: | Postgraduate Medical Journal. 45:583-590 |
| ISSN: | 1469-0756 0032-5473 |
| DOI: | 10.1136/pgmj.45.527.583 |
| Popis: | Summary A series of fourteen patients with polycythaemia due to hypoxic lung disease has been treated with a combination of phenylhydrazine hydrochloride and pyrimethamine to reduce the haematocrit level, with doses usually of up to 100 mg/day (and rarely up to 150 mg/day) of the former and never more than 12·5 mg/day of the latter. Successful reduction of the haematocrit level was achieved in every case without any significant thrombocytopenia, the lowest level ever occurring being 100,000 platelets/mm3 in two patients. All the patients were improved symptomatically. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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