Occupational Exposure in the Lombardy Region (Italy) to SARS-CoV-2 Infection: Results from the MUSTANG–OCCUPATION–COVID-19 Study
| Autor: | Valle P. D., Fabbri M., Madotto F., Ferrara P., Cozzolino P., Calabretto E., D'orso M. I., Longhi E., Polosa R., Riva M. A., Mazzaglia G., Sommese C., Mantovani L. G., Agazzi G., Anzaldi E., Berardi C., Beretta P., Clemente F., Crotti G., Harari S., Lorelli S., Mancino M., Pedretti R. F. E., Polizzotti G., Raucci P., Spatafora C., Squassabia G., Staine T., Zuccato C. |
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| Přispěvatelé: | Valle, P, Fabbri, M, Madotto, F, Ferrara, P, Cozzolino, P, Calabretto, E, D'Orso, M, Longhi, E, Polosa, R, Riva, M, Mazzaglia, G, Sommese, C, Mantovani, L, Agazzi, G, Anzaldi, E, Berardi, C, Beretta, P, Clemente, F, Crotti, G, Harari, S, Lorelli, S, Mancino, M, Pedretti, R, Polizzotti, G, Raucci, P, Spatafora, C, Squassabia, G, Staine, T, Zuccato, C |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Health
Toxicology and Mutagenesis Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lcsh:Medicine Context (language use) 030204 cardiovascular system & hematology Antibodies Viral Article Immunoglobulin G Persistence (computer science) 03 medical and health sciences 0302 clinical medicine Humans Medicine Seroprevalence 030212 general & internal medicine Occupations antibody persistence Disease burden biology seroprevalence business.industry SARS-CoV-2 lcsh:R Public Health Environmental and Occupational Health COVID-19 occupational exposure Italy biology.protein Observational study Antibody business Demography |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 18 Issue 5 International Journal of Environmental Research and Public Health, Vol 18, Iss 2567, p 2567 (2021) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph18052567 |
| Popis: | Sero-epidemiological surveys are valuable attempts to estimate the circulation of SARS-CoV-2 in general or selected populations. Within this context, a prospective observational study was conducted to estimate the prevalence and persistence of SARS-CoV-2 antibodies in different categories of workers and factors associated with positivity, through the detection of virus-specific immunoglobulin G and M (IgG/IgM) in serum samples. Enrollees were divided in low exposure and medium-high groups on the basis of their work activity. Antibody responders were re-contacted after 3 months for the follow-up. Of 2255 sampled workers, 4.8% tested positive for SARS-CoV-2 IgG/IgM antibodies, with 81.7% to IgG only. Workers who continued to go to their place of work, were healthcare workers, or experienced at least one COVID-19-related symptom were more likely to test positive for SARS-CoV-2 antibodies. SARS-CoV-2 antibodies prevalence was significantly higher in the medium-high risk vs. low-risk group (7.2% vs. 3.0%, p < 0.0001). At 3-month follow-up, 81.3% of subjects still had antibody response. This study provided important information of SARS-CoV-2 infection prevalence among workers in northern Italy, where the impact of COVID-19 was particularly intense. The presented surveillance data give a contribution to refine current estimates of the disease burden expected from the SARS-CoV-2. |
| Databáze: | OpenAIRE |
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