Cheilitis glandularis: case report and systematic literature review

Autor: Sarah Campos de Sales, Sicília Rezende Oliveira, Erika Soares Pantuzzo, Fernanda Pereira Delgado Costa, Marcus Henrique Xavier, Ricardo Alves de Mesquita, Lucas Guimarães Abreu, Felipe Eduardo Baires Campos, Wagner Henriques de Castro, Tarcília Aparecida Silva
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Dermatology. 62:154-168
ISSN: 1365-4632
0011-9059
Popis: Cheilitis glandularis (CG) is a rare inflammatory disease of unknown etiology that affects the minor salivary glands predominantly in the lower lip. In this article, we report the case of an 18-year-old black woman who presented with a deep suppurative type of CG in both lips. In addition, we performed a systematic literature review in five databases (PubMed, Scopus, Web of Science, Ovid, and Embase) to identify CG case reports or case series. A total of 360 references were retrieved in the electronic databases. Thirty-four articles met the inclusion criteria, and six were retrieved through manual search, totaling 40 articles included in the systematic review. Thirty-nine (68.4%) cases occurred in male individuals and 18 (31.6%) in female individuals. The mean age of affected individuals was 40.9 years. Different clinical manifestations ranging from no symptoms to discomfort, pain, swelling, erythema, eversion of the lip, dilated ductal openings, ulcers, and crust have been reported. Among the included CG cases, 41 affected exclusively the lower lip (71.9%). In four cases, the CG only affected the upper lip (7.0%). In 12 cases, the lesion affected both the lower and upper lips (21.1%). Different treatment modalities were adopted in the management of CG. Although the surgical treatment was indicated (42.1%), the conservative treatment with topical medications, as in the present case, resulted in resolution in 21.0% of cases.
Databáze: OpenAIRE
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