Comparative study of serum lipid levels in normotensive and pre-eclamptic Nigerian women
| Autor: | Oladapo Olayemi, Theresa Azonima Irinyenikan, Ayo O Arowojolu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pregnancy Proteinuria Serum lipids hypertension pre-eclampsia normotensive women Nigerian women Triglyceride Cholesterol Obstetrics business.industry Case-control study Blood lipids Venous blood medicine.disease Preeclampsia chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine lipids (amino acids peptides and proteins) medicine.symptom business |
| Zdroj: | International Journal of Medicine and Biomedical Research; Vol 3, No 2 (2014); 137-145 |
| ISSN: | 2277-0941 2315-5019 |
| Popis: | Background : Pre-eclampsia is a common syndrome that occurs in the second half of pregnancy and often manifest with hypertension and significant proteinuria. It occurs in up to 10% of pregnancies and is the second cause of maternal mortality worldwide accounting for 17% of maternal deaths in Nigeria. Aim : This study was performed to compare the serum lipid levels of pregnant normotensive and pre-eclamptic women. Methods : It was a case control study involving 50 normotensive and 50 preeclamptic women at the University College Hospital, Ibadan, making a total of 100 participants. Their venous blood (5mls) was collected after an overnight fast of 8-12 hours and this was analysed for cholesterol, triglyceride, high density lipoprotein-cholesterol (HDL-C), very low density lipoprotein-cholesterol (VLDL-C) and low density lipoprotein-cholesterol (LDL-C) using standard enzymatic methods. Results : The study showed that there was a significantly higher levels of triglyceride, VLDL-C and HDLC in the pre-eclamptic compared to the normotensive group (P Conclusion : Lipids therefore have an important role in the aetiopathogenesis of pre-eclampsia and could be estimated during the conservative management of patients with preeclampsia. Key Words : Serum lipids; hypertension; pre-eclampsia; normotensive women; Nigerian women |
| Databáze: | OpenAIRE |
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