Longitudinal changes in quality of life following ICD implant and the impact of age, gender, and ICD shocks: observations from the INTRINSIC RV trial
| Autor: | Samuel F. Sears, Scott Brown, Rakesh Gopinathannair, Darin R. Lerew, Brian Olshansky, Natalie J. Cross |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Randomization medicine.medical_treatment Population 030204 cardiovascular system & hematology Angina 03 medical and health sciences 0302 clinical medicine Patient satisfaction Age Distribution Quality of life Physiology (medical) Prevalence Medicine Humans 030212 general & internal medicine Longitudinal Studies Sex Distribution education Survival rate Aged Aged 80 and over Heart Failure education.field_of_study business.industry Middle Aged Implantable cardioverter-defibrillator medicine.disease humanities United States Defibrillators Implantable Electric Injuries Survival Rate Treatment Outcome Patient Satisfaction Health Care Surveys Cohort Physical therapy Quality of Life Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 48(3) |
| ISSN: | 1572-8595 |
| Popis: | ICDs can improve survival in at-risk patients but no consensus exists with respect to their impact on health-related quality of life (QOL). Moreover, the data are unclear on QOL benefits in specific patient subgroups. We sought to analyze, in the INTRINSIC RV ICD trial population, health-related QOL longitudinally following ICD implant and consider impact of age, gender, and ICD shocks on QOL by employing a global measure of health-related QOL. One thousand five hundred thirty patients had an ICD implanted. One week after implant (n = 1461), 988 patients were randomized to DDDR with AV search hysteresis (n = 502) or VVI (n = 486) programming. QOL data, using the SF-36 short form, were obtained for the 1461 patient cohort, irrespective of randomization status, at baseline and prospectively for 1 year following ICD implant. Longitudinal mixed-effect analyses revealed significant improvements from baseline across all SF-36 subscales and component scores for the overall study cohort. Women had a substantially lower QOL at baseline, although their improvement after implant was similar to men. Patients |
| Databáze: | OpenAIRE |
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