Critical illness polyneuropathy and myopathy in a rural area in Vietnam
| Autor: | Luan Nguyen The, Cong Nguyen Huu |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Rural Population medicine.medical_specialty Critical Illness Myopathy law.invention Polyneuropathies Muscular Diseases law Internal medicine Humans Medicine Longitudinal Studies Prospective Studies Critical illness polyneuropathy Prospective cohort study Aged Aged 80 and over business.industry Mortality rate Incidence (epidemiology) Middle Aged medicine.disease Intensive care unit Systemic inflammatory response syndrome Vietnam Neurology Physical therapy Female Neurology (clinical) business Polyneuropathy |
| Zdroj: | Journal of the Neurological Sciences. 357:276-281 |
| ISSN: | 0022-510X |
| Popis: | Introduction Critical illness polyneuropathy, myopathy and polyneuromyopathy, grouped under the term CIP/CIM, share several risk factors and are associated with debilitating outcomes. Objective To assess the incidence and distribution of CIP/CIM subtypes and evaluate the risk factors and outcomes of CIP/CIM in a rural hospital in Vietnam. Method One hundred and thirty three critically ill patients treated more than ten days in the ICU were enrolled. The Medical Research Council (MRC) sum scores and the Overall Neuropathy Limitations Scale (ONLS) score were calculated and risk factors were monitored. Extensive electrodiagnostic investigations were performed to confirm the diagnosis of CIP/CIM. Results CIP/CIM was diagnosed in 73 (55%) patients. The distribution of polyneuropathy, myopathy and polyneuromyopathy was 35 (48%), 16 (22%) and 22 (30%), respectively. Independent risk factors included systemic inflammatory response syndrome, shock, and electrolyte disturbances. Compared to patients without CIP/CIM, patients with CIP/CIM experienced a mortality rate of 49% vs. 30%, a length of stay in ICU of 20.3 days vs. 14.3 days, an ONLS score at day thirty of 4.2 vs. 1.3 and at day ninety of 2.7 vs. 1.8. Conclusion The study revealed that the diagnosis of CIP/CIM was associated with significantly poorer outcomes in comparison to controls. |
| Databáze: | OpenAIRE |
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