Guaianolides from Tanacetopsis karataviensis (Kovalevsk.) Kovalevsk
| Autor: | D. E. Dusmatova, H. Gildenast, V. V. Uzbekov, Kh. М. Bobakulov, Ulli Englert, N. D. Аbdullaev, Kambarali K. Turgunov, I. D. Sham'yanov, R. F. Мukhamatkhanova, B. Tashkhojaev, V. P. Bruskov |
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| Rok vydání: | 2022 |
| Předmět: |
010405 organic chemistry
Organic Chemistry Plant Science Nuclear magnetic resonance spectroscopy Sesquiterpene 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Phytochemical Organic chemistry X ray analysis |
| DOI: | 10.6084/m9.figshare.12895981.v3 |
| Popis: | In continuation of our phytochemical study on the aerial part of Tanacetopsis karataviensis (Kovalevsk.) Kovalevsk, three new guaiane-type sesquiterpene lactones were isolated namely karatanolide (1), 11,13β-dihydrokaratanolide (2) and 11,13α-dihydrokaratanolide (3), in addition to the two known sesquiterpene lactones 1β,10α-dihydroxyarglabin (4) and artefin (5). The structures of the isolated sesquiterpene lactones were elucidated by IR and NMR spectroscopy. Single crystal X-ray diffraction allowed to unambiguously confirm the structure of the isolated sesquiterpene lactones. Quantum chemical calculations of the guaianolides 1–3 suggested the existence of two conformations for the seven-membered cycle. All sesquiterpene lactones from Tanacetopsis karataviensis were isolated for the first time. |
| Databáze: | OpenAIRE |
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