Modelling haemoglobin incremental loss on chronic red blood cell transfusions

Autor: Phillip W. Carter, Andrew J. Dunham
Rok vydání: 2022
Předmět:
Zdroj: Vox sanguinisREFERENCES. 117(6)
ISSN: 1423-0410
Popis: Understanding the impact of red blood cell (RBC) lifespan, initial RBC removal, and transfusion intervals on patient haemoglobin (Hb) levels and total iron exposure is not accessible for chronic transfusion scenarios. This article introduces the first model to help clinicians optimize chronic transfusion intervals to minimize transfusion frequency.Hb levels and iron exposure from multiple transfusions were calculated from Weibull residual lifespan distributions, the fraction effete RBC removed within 24-h (XIncreased XSystematic trends in fractional Hb incremental loss X
Databáze: OpenAIRE
Nepřihlášeným uživatelům se plný text nezobrazuje