Peculiarities of Antithyroid Autoimmunity Indicators in Type 2 Diabetic Patients Depending on Leptin Level in Blood Serum and Their Dynamics as a Result of Sodium Selenite Treatment
| Autor: | N.O. Abramova, M.S. Berezova, N.V. Pashkovska |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
diabetes mellitus type 2
endocrine system medicine.medical_specialty endocrine system diseases medicine.medical_treatment medicine.disease_cause leptin lcsh:Diseases of the endocrine glands. Clinical endocrinology Autoimmunity Blood serum Thyroid peroxidase Diabetes mellitus Internal medicine medicine selenium antithyroid antibodies lcsh:RC648-665 biology business.industry Leptin Thyroid Antibody titer medicine.disease medicine.anatomical_structure Endocrinology biology.protein Thyroglobulin business САХАРНЫЙ ДИАБЕТ 2-ГО ТИПА DIABETES MELLITUS TYPE 2 ЛЕПТИН LEPTIN АНТИТИРЕОИДНЫЕ АНТИТЕЛА ANTITHYROID ANTIBODIES СЕЛЕН SELENIUM ЦУКРОВИЙ ДіАБЕТ 2-ГО ТИПУ АНТИТИРЕОїДНі АНТИТіЛА |
| Zdroj: | Mìžnarodnij Endokrinologìčnij Žurnal, Vol 11, Iss 1.65, Pp 9-12 (2015) |
| ISSN: | 2307-1427 2224-0721 |
| Popis: | There were studied 46 patients with diabetes mellitus type 2 in order to identify the autoimmune processes directed against thyroid tissue and dependence of those changes on the level of leptin in blood serum. It was established that in patients with high leptin serum level antithyroid antibody titer increased. In order to adjust the levels of antithyroid antibodies sodium selenite was prescribed against the background of standard therapy. Statistically significant reduction in antibodies expression to thyroglobulin and thyroperoxidase after treatment with sodium selenite dosed 50 mg after a month has been found. |
| Databáze: | OpenAIRE |
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