Occupational and non-occupational allergic contact dermatitis : a follow-up study
| Autor: | Veda Marija Varnai, Sanja Kežić, Davor Rimac, Jelena Macan |
|---|---|
| Přispěvatelé: | Amsterdam Public Health, Coronel Institute of Occupational Health |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Rhinitis Allergic Perennial Genotype Eczema Non occupational occupational contact dermatitis prognosis prevention of occupational skin diseases asymptomatic contact sensitization patch testing Dermatology Filaggrin Proteins Patch testing Dermatitis Atopic Intermediate Filament Proteins Predictive Value of Tests parasitic diseases medicine Humans Occupational contact dermatitis Allergic contact dermatitis business.industry Clinical course Follow up studies Middle Aged Patch Tests Prognosis medicine.disease Rhinitis Allergic Asthma Dermatitis Occupational Dermatitis Allergic Contact Mutation Female business Follow-Up Studies |
| Zdroj: | Dermatology (Basel, Switzerland), 227(4), 321-329. S. Karger AG |
| ISSN: | 1018-8665 |
| Popis: | Background/Aims: The aim of this study was to obtain insight into the clinical course and prognosis of allergic contact dermatitis (ACD), including potential effects of genetic and environmental factors. Methods: Eighty-two patients with previously defined ACD acquired occupationally (OACD) or non-occupationally (NOACD) were patch retested and evaluated for the presence of persistent eczema, atopy and filaggrin mutations. Results: The crude risk for the persistence of a positive patch test (PT) reaction was 6.3 times higher (95% CI 3.63-11.0) for PT reactions assessed as ‘+++' compared to ‘++' reactions at the first PT. Among the categories of OACD, NOACD, age, gender, atopy, and the number of positive PT reactions at the first and second PT, only OACD (OR 10.0, 95% CI 1.95-51.2) and number of positive PT reactions at retesting (OR 3.85, 95% CI 1.57-9.44) were found to be predictors of persistent eczema. Conclusions: Occupationally acquired contact allergy was emphasized as the most important factor in predicting poor prognosis of ACD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|