A Comparison of Corneal Endothelial Cell Changes After 1-Site and 2-Site Phacotrabeculectomy
| Autor: | Mohammad Rahnavardi, Nariman Nassiri, Nader Nassiri, Laleh Rahmani |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Intraocular pressure medicine.medical_specialty Visual acuity medicine.medical_treatment Visual Acuity Glaucoma Cell Count Trabeculectomy Cataract Corneal Diseases Cohort Studies Postoperative Complications Ophthalmology medicine Humans Eye surgery Intraocular Pressure Aged Phacoemulsification business.industry Endothelium Corneal medicine.disease Single surgeon cardiovascular system Female Corneal endothelial cell medicine.symptom business Follow-Up Studies |
| Zdroj: | Cornea. 27:889-894 |
| ISSN: | 0277-3740 |
| Popis: | PURPOSE To compare the corneal endothelial cell (CEC) changes that occurred after phacotrabeculectomy performed at 1 or 2 sites. DESIGN A historical cohort study. METHODS The records of patients who had 1-site (n = 61) or 2-site (n = 52) limbus-based phacotrabeculectomy over a 4-year period (2002-2005) at 1 eye surgery center (Vanak Eye Surgery Center, Tehran, Iran) by a single surgeon were reviewed, and postoperative CEC indices were measured. Preoperative CEC indices, performed for a then-ongoing trial, were compared with postoperative measurements of the last follow-ups. The main outcome measure was endothelial cell count. RESULTS The median follow-up time was 12 months (range 9-24 months). There was no difference between the operations in improving visual acuity, lowering intraocular pressure, and decreasing the number of antiglaucoma medications required. However, 2-site surgery was associated with significantly more expansion in the CEC area (P < 0.001). On multivariate analysis, longer follow-up, 2-site surgery, and grade 4 cataract density were independently associated with more CEC loss, and longer follow-up, 2-site surgery, and steroid-induced glaucoma were associated with CEC area expansion. Postoperative complications were not markedly different between the 2 groups. CONCLUSIONS In both groups, the longer the follow-up time was, the higher the CEC loss and the CEC area expansion were. One-site surgery seems to cause less CEC damage than the 2-site operation during the median follow-up time of 1 year. |
| Databáze: | OpenAIRE |
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