Velocity Pulsatility and Arterial Distensibility Along the Internal Carotid Artery

Autor: Birgitta K. Velthuis, Jaco J.M. Zwanenburg, Rick J. van Tuijl, Gabriel J.E. Rinkel, Irene C. van der Schaaf, Ynte M. Ruigrok
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Arterial velocity
Adult
Male
medicine.medical_specialty
Aging
Magnetic Resonance Imaging (MRI)
internal carotid artery
Pulse Wave Analysis
Age and sex
Pulsatility index
Carotid siphon
030218 nuclear medicine & medical imaging
Imaging
03 medical and health sciences
Young Adult
0302 clinical medicine
Sex Factors
Internal medicine
medicine.artery
MRI angiography
velocity pulsatility index
Carotid canal
Medicine
cerebral hemodynamics
Humans
Original Research
Aged
medicine.diagnostic_test
business.industry
Hemodynamics
Angiography
Age Factors
Magnetic resonance imaging
Middle Aged
Magnetic Resonance Imaging
Vasodilation
medicine.anatomical_structure
Cerebral hemodynamics
Basilar Artery
Cardiology
Female
Internal carotid artery
distensibility
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
Blood Flow Velocity
Carotid Artery
Internal
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
ISSN: 2047-9980
Popis: Background Attenuation of velocity pulsatility along the internal carotid artery (ICA) is deemed necessary to protect the microvasculature of the brain. The role of the carotid siphon within the whole ICA trajectory in pulsatility attenuation is still poorly understood. This study aims to assess arterial variances in velocity pulsatility and distensibility over the whole ICA trajectory, including effects of age and sex. Methods and Results We assessed arterial velocity pulsatility and distensibility using flow‐sensitized 2‐dimensional phase‐contrast 3.0 Tesla magnetic resonance imaging in 118 healthy participants. Velocity pulsatility index (vPI=(V max −V min )/V mean ) and arterial distensibility defined as area pulsatility index (A max −A min )/A mean ) were calculated at C1, C3, and C7 segments of the ICA. vPI increased between C1 and C3 (0.85±0.13 versus 0.93±0.13, P P P P P Conclusions Along the whole ICA trajectory, vPI increased from extracranial C1 up to the carotid siphon C3 with overall no effect on vPI between extracranial C1 and intracranial C7 segments. This suggests that the bony carotid canal locally limits the arterial distensibility of the ICA, increasing the vPI at C3 which is consequently decreased again over the carotid siphon. In addition, vPI in men is higher and increases with age.
Databáze: OpenAIRE
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