| Popis: |
A simple, precise, and accurate spectrophotometric method has been developed and validated for the estimation of Enrofloxacin in bulk as well as tablet formulation. The UV spectra of Enrofloxacin were obtained in 0.1N HCl and 0.1N NaOH, and the overlain spectra showed maximum absorbance at 271.0 nm (maxima) and 276.5 nm (minima) in 0.1N NaOH and HCl respectively. The drug follows linearity in the range of 5-30 µg/ml (R2= 0.988). Both intra- and inter-day precision showed % RSD˂ 2 while LOD, and LOQ were 0.320 and 0.971 respectively. The method was validated as per ICH guidelines. Keywords: Enrofloxacin, Differential UV Spectrophotometry, Validation, ICH, Enrofloxacin Tablet Analysis, etc. |
