The distributions of hematologic and biochemical values in healthy high-school adolescents in Japan
Autor: | Masaaki Mori, Yasunori Sato, Tatsuhiko Azegami, Nobuko Yamada-Goto, Tomoyasu Nishimura, Ayano Murai-Takeda |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Male
030213 general clinical medicine Percentile Epidemiology Physiology Disease 030204 cardiovascular system & hematology Adolescents Biochemistry Pediatrics Geographical Locations Disease susceptibility chemistry.chemical_compound Families 0302 clinical medicine Japan Reference Values Medicine and Health Sciences Medicine Public and Occupational Health Children education.field_of_study Multidisciplinary Hematologic Tests Schools Child Health Hematology Lipids Chemistry Cholesterol Creatinine Physical Sciences Female Research Article Asia Adolescent Science Population 03 medical and health sciences Humans education business.industry Serum uric acid Cholesterol HDL Chemical Compounds Biology and Life Sciences Reference intervals Uric Acid chemistry Age Groups Medical Risk Factors People and Places Uric acid Population Groupings business Acids Biomarkers Blood Chemical Analysis |
Zdroj: | PLoS ONE PLoS ONE, Vol 15, Iss 11, p e0242272 (2020) |
ISSN: | 1932-6203 |
Popis: | Laboratory tests of adolescents are often interpreted by using reference intervals derived from adults, even though these populations differ in their physical and physiologic characteristics and disease susceptibility. Therefore, to examine the distribution of laboratory values specific for adolescents, we analyzed hematologic and biochemical measurements obtained from 12,023 healthy Japanese adolescents (ages 15 through 18 years; male, 9165; female, 2858) during 2009 through 2018. Distributions were shown as medians with 95% (2.5th and 97.5th percentiles) of values and were compared with those from previous studies that examined similar Asian populations. There were some differences between hematologic parameters, serum creatinine and uric acid concentration, and lipid levels of Japanese adults and adolescents. In comparison with other Asian populations, the distributions of serum uric acid and high-density–lipoprotein cholesterol in the present study were slightly higher than those in the other studies. Although further research is need, the distributions of hematologic and biochemical tests in adolescents may have the potential to facilitate the early identification and management of disease in this population. |
Databáze: | OpenAIRE |
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