Predictive Factors of Restenosis After Coronary Stent Placement
| Autor: | Franz-Josef Neumann, Helmut Schühlen, Adnan Kastrati, Martin Hadamitzky, Josef Dirschinger, Shpend Elezi, Jörg Hausleiter, Albert Schömig, Hanna Walter, Anne Wehinger |
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| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Coronary Disease Coronary Angiography Diabetes Complications Coronary artery bypass surgery Restenosis Recurrence Risk Factors Internal medicine Angioplasty Coronary stent medicine Humans Angioplasty Balloon Coronary Risk factor Aged Analysis of Variance medicine.diagnostic_test business.industry Odds ratio Middle Aged medicine.disease Angiography Cardiology Regression Analysis Female Stents Radiology Cardiology and Cardiovascular Medicine business Complication Follow-Up Studies |
| Zdroj: | Journal of the American College of Cardiology. 30:1428-1436 |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/s0735-1097(97)00334-3 |
| Popis: | Objectives. The objective of this study was to identify clinical, lesional and procedural factors that can predict restenosis after coronary stent placement.Background. Coronary stent placement reduces the restenosis rate compared with that after percutaneous transluminal coronary angioplasty (PTCA). However, restenosis remains an unresolved issue, and identification of its predictive factors may allow further insight into the underlying process.Methods. All patients with successful coronary stent placement were eligible for this study unless they had had a major adverse cardiac event during the 1st 30 days after the procedure. Of the 1,349 eligible patients (1,753 lesions), follow-up angiography at 6 months was performed in 80.4% (1,084 patients, 1,399 lesions). Demographic, clinical, lesional and procedural data were prospectively recorded and analyzed for any predictive power for the occurrence of late restenosis after stenting. Restenosis was evaluated by using three outcomes at follow-up: binary restenosis as a diameter stenosis ≥50%, late lumen loss as lumen diameter reduction and target lesion revascularization (TLR) as any repeat PTCA or coronary artery bypass surgery involving the stented lesion.Results. Multivariate analysis demonstrated that diabetes mellitus, placement of multiple stents and minimal lumen diameter (MLD) immediately after stenting were the strongest predictors of restenosis. Diabetes increased the risk of binary restenosis with an odds ratio (OR) [95% confidence interval] of 1.86 [1.56 to 2.16] and the risk of TLR with an OR of 1.45 [1.11 to 1.80]. Multiple stents increased the risk of binary restenosis with an OR of 1.81 [1.55 to 2.06] and that of TLR with an OR of 1.94 [1.66 to 2.22]. An MLD |
| Databáze: | OpenAIRE |
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