Primary localized amyloidosis presenting as diffuse amorphous calcified mass in both orbits: case report
| Autor: | Allan Christian Pieroni Gonçalves, Rodrigo Moritz, Mário Luiz Ribeiro Monteiro |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Pathology
medicine.medical_specialty Exophthalmos Exoftalmo Oftalmoplegia Amiloidose Diagnosis Differential Immunoglobulin Light-chain Amyloidosis lcsh:Ophthalmology Feminino Biopsy Eosinophilic Orbital Diseases medicine Humans Doenças orbitárias Meia-idade Hyaline Relato de caso medicine.diagnostic_test business.industry Amyloidosis Calcinosis General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Imagem por ressonância magnética eye diseases Humanos Ophthalmology medicine.anatomical_structure lcsh:RE1-994 Female medicine.symptom Tomography X-Ray Computed business Orbit (anatomy) Calcification |
| Zdroj: | Arquivos Brasileiros de Oftalmologia, Vol 74, Iss 5, Pp 374-376 (2011) |
| ISSN: | 1678-2925 |
| Popis: | Primary localized amyloidosis is rare in the orbit. We report the case of a 63-year-old woman that presented with bilateral proptosis and ophthalmoplegia. A computed tomography scan revealed an infiltrative amorphous and markedly calcified mass in both orbits while a magnetic resonance scan showed a heterogeneous hypointense signal on T2-weighted images. A biopsy was performed through an anterior orbitotomy. Microscopy revealed extracellular amorphous and eosinophilic hyaline material which stained pink with Congo red and displayed green birefringence on polarized microscopy, leading to a diagnosis of amyloidosis. The results of the systemic workup were completely normal. A two-year follow-up period without any treatment disclosed no worsening of the condition. While calcification of nonvascular orbital lesions has often been regarded as suggestive of malignant disease, our case is a reminder that it can also be a characteristic presenting sign of orbital amyloidosis. |
| Databáze: | OpenAIRE |
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