Bile formation and secretion: An update
| Autor: | Carol J. Soroka, James L. Boyer |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Hepatology Bile Canaliculi Biology Cholangiocyte Bile flow Bile Acids and Salts 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Liver Bile formation Animals Bile Humans 030211 gastroenterology & hepatology Identification (biology) Membrane vesicle Secretion Biliary Tract Neuroscience |
| Zdroj: | Journal of hepatology. 75(1) |
| ISSN: | 1600-0641 |
| Popis: | Summary Bile formation is a fundamental physiological process that is vital to the survival of all vertebrates. However, little was known about the mechanisms of this secretion until after World War II. Initial studies involved classic physiologic studies in animal models and humans, which progressed to include studies in isolated cells and membrane vesicles. The advent of molecular biology then led to the identification of specific transport systems that are the determinants of this secretion. Progress in this field was reviewed in the American Physiologic Society’s series on “Comprehensive Physiology” in 2013. Herein, we provide an in-depth update of progress since that time. |
| Databáze: | OpenAIRE |
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