Effects of testicular dysgenesis syndrome components on testicular germ cell tumor prognosis and oncological outcomes
| Autor: | Selcuk Sarikaya, Ismail Selvi, Halil Başar, Taha Numan Yıkılmaz, Erdem Öztürk |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Urology 030232 urology & nephrology Testicular Germ Cell Tumor Semen 03 medical and health sciences 0302 clinical medicine Cryptorchidism medicine Testicular dysgenesis syndrome Testicular cancer Cell Tumor [Supplementary Concept] Anamnesis Fetus Hypospadias business.industry medicine.disease Diseases of the genitourinary system. Urology Testicular Germ Radical orchiectomy 030220 oncology & carcinogenesis RC870-923 business |
| Zdroj: | International Brazilian Journal of Urology, Vol 46, Iss 5, Pp 725-740 (2020) International braz j urol v.46 n.5 2020 International Braz J Urol Sociedade Brasileira de Urologia (SBU) instacron:SBU International braz j urol, Volume: 46, Issue: 5, Pages: 725-740, Published: 31 JUL 2020 |
| ISSN: | 1677-6119 |
| Popis: | Purpose: To evaluate whether components of Testicular Dysgenesis Syndrome (TDS) affect testicular germ cell tumor (TGCT) prognosis and oncological outcomes. According to the hypothesis called TDS; undescended testis, hypospadias, testicular cancer and spermatogenic disorders share the same risk factors and have a combined fetal origin. Materials and Methods: We retrospectively evaluated the stages and oncological outcomes of 69 patients who underwent radical orchiectomy between January 2010 and December 2014 due to TGCT in our department. The presence of undescended testis, hypospadias and semen parameters disorders were recorded according to anamnesis of patients. Results: Among 69 patients with TGCT, only 16 (23.1%) had TDS. Significantly higher rate of TDS (36.1% vs. 9.1%) was observed at the advanced stages of TGCT(p=0.008). In the TDS group, the rates of local recurrence (50% vs. 11.3%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|