Drug Allergy Clinical Characteristics in Pediatrics
| Autor: | Vycke Yunivita Kusumah Dewi, Gartika Sapartini, R. Devina Fathia Almira |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Drug
Pediatrics medicine.medical_specialty Allergy media_common.quotation_subject Drug allergy lcsh:Medicine 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Erythema multiforme Exanthem media_common Clinical manifestation drug allergy pediatric lcsh:R5-920 business.industry Medical record lcsh:R General Medicine medicine.disease Drug eruption Penicillin 030228 respiratory system lcsh:Medicine (General) business medicine.drug |
| Zdroj: | Althea Medical Journal, Vol 4, Iss 2, Pp 299-303 (2017) |
| ISSN: | 2337-4330 |
| DOI: | 10.15850/amj.v4n2.1097 |
| Popis: | Background: A drug allergy causes a morbidity and a mortality due to its various range of clinical manifestation. Unfortunately, a study focusing in pediatric drug allergy is insufficient, especially in Bandung. Thus, this study is conducted to determine the clinical characteristic of pediatric drug allergy in Dr. Hasan Sadikin General Hospital Bandung. Methods: This study was a retrospective descriptive study using medical records of pediatric drug allergy patients between 2010–2015 in Dr. Hasan Sadikin General Hospital Bandung taken with total sampling method. The variables were patient age, gender, causative drug, and clinical manifestation. Clinical manifestation was then divided into exanthem, urticaria, erythema multiforme, Steven-Johnson’s syndrome/toxic epidemiolytic necrosis (SJS/TEN), and fixed drug eruption (FDE). Results: Out of 101 patients, only 71 were included in the study due to incomplete medical records of the rest. There were 34 (47.89%) males and 37 (52.11%) females. Patients’ age ranged from 1–18 years old with the mean of 7.4 years old. The most common clinical manifestation was SJS/TEN with 25 (35.21%) patients, followed by exanthem with 22 (30.98%) patients. The most common suspected causative drug was non-steriodal anti inflammatory drugs (NSAID) (24%), followed with penicillin (21%). Conclusions: Most common manifestation of pediatric drug allergy in female is SJS/TEN, meanwhile in male is exanthema. Steven-Johnson’s syndrome/toxic epidemiolytic necrosis mostly occurs at the age group of 12–18 years old, and exanthema at the age group of 0–3 years old. This condition is mostly caused by NSAID and penicillin . DOI: 10.15850/amj.v4n2.1097 |
| Databáze: | OpenAIRE |
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