Tunicates as a biocontrol tool for larvicides acute toxicity of Zika virus vector Aedes aegypti
| Autor: | Umamaheswari Sundaresan, Satheesh Kumar Palanisamy, Velusamy Arumugam, Manigandan Venkatesan, Saravanan Ramachandran, Nishakavya Saravanan, Karthi Sengodan |
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| Rok vydání: | 2019 |
| Předmět: |
biology
fungi Biological pest control Aedes aegypti Environmental Science (miscellaneous) biology.organism_classification Agricultural and Biological Sciences (miscellaneous) Acute toxicity Microbiology Zika virus Short Reports Biological property Chemical constituents Gas chromatography–mass spectrometry Didemnum Biotechnology |
| Zdroj: | 3 Biotech |
| ISSN: | 2190-5738 2190-572X |
| DOI: | 10.1007/s13205-019-1699-3 |
| Popis: | In this present study, we conducted untargeted metabolic profiling using gas chromatography–mass spectrometry (GC–MS) analysis of ascidian Didemnum bistratum to assess the chemical constituents by searching in NIST library with promising biological properties against anti-bacterial and Zika virus vector mosquitocidal properties. Metabolites, steroids and fatty acids are abundant in crude compounds of ascidian D. bistratum and showed potential zone growth inhibition against bacterial strains Kluyvera ascorbate (10 mm). The active crude compounds of D. bistratum exhibited prominent larvicidal activity against the Zika vector mosquitoes of Aedes aegypti (LC(50) values of 0.44 mg/ml) and Cluex quinquefasciatus (LC(50) values of 2.23 mg/ml). The findings of this study provide a first evidence of the biological properties exhibited by D. bistratum extracts, thus increasing the knowledge about the Zika virus vector mosquitocidal properties of ascidian. Overall, ascidian D. bistratum is promising and biocontrol or eco-friendly tool against A. aegypti and C. quinquefasciatus with prospective toxicity against non-target organisms. |
| Databáze: | OpenAIRE |
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