Fentanyl-induced asystole in two dogs

Autor: Won-gyun Son, Inhyung Lee, Moonjung Jang
Rok vydání: 2015
Předmět:
Zdroj: Journal of Small Animal Practice. 56:411-413
ISSN: 0022-4510
DOI: 10.1111/jsap.12312
Popis: Fentanyl is used in small animals for perioperative analgesia during anaesthesia. Severe bradycardia and asystole were observed on bolus administration of a 3 µg/kg loading dose of fentanyl in two dogs under isoflurane anaesthesia. Premedication with 10 µg/kg glycopyrrolate did not prevent asystole in the first case; and although bradycardia was treated with 5 µg/kg glycopyrrolate administered intravenously in the second case, the heart rate continuously decreased and asystole subsequently developed. Asystole in both cases was quickly corrected by intravenous administration of 0 · 04 mg/kg atropine and closed chest compressions. This case report describes asystole induced by fentanyl administration in isoflurane anaesthetised dogs. Atropine was more effective than glycopyrrolate in the treatment of fentanyl-induced asystole.
Databáze: OpenAIRE