Probiotic mixture VSL#3: An overview of basic and clinical studies in chronic diseases
| Autor: | Dan Pan, Bing Chang, Min Jiang, Li-Xuan Sang, Fang-Shu Cheng |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Medical food
Review Intestinal barrier function Hepatic Diseases law.invention 03 medical and health sciences Probiotic 0302 clinical medicine law Diabetes mellitus medicine Intestinal microbial balance Mechanism (biology) business.industry Probiotic mixture VSL#3 VSL#3 Therapeutic use Cytokine expression Correction Microbial composition General Medicine medicine.disease Obesity 030220 oncology & carcinogenesis Chronic diseases Immunology Cytokines 030211 gastroenterology & hepatology business |
| Zdroj: | World Journal of Clinical Cases |
| ISSN: | 2307-8960 |
| Popis: | Probiotics are known as "live microorganisms" and have been proven to have a health effect on hosts at the proper dose. Recently, a kind of probiotic mixture including eight live bacterial strains, VSL#3, has attracted considerable attention for its combined effect. VSL#3 is the only probiotic considered as a kind of medical food; it mainly participates in the regulation of the intestinal barrier function, including improving tight junction protein function, balancing intestinal microbial composition, regulating immune-related cytokine expression and so on. The objective of this review is to discuss the treatment action and mechanism for the administration of VSL#3 in chronic diseases of animals and humans (including children). We found that VSL#3 has a therapeutic or preventive effect in various systemic diseases per a large number of studies, including digestive systemic diseases (gastrointestinal diseases and hepatic diseases), obesity and diabetes, allergic diseases, nervous systemic diseases, atherosclerosis, bone diseases, and female reproductive systemic diseases. |
| Databáze: | OpenAIRE |
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