Outcome of retinoblastoma in east Africa
| Autor: | J. Luande, Milka Mafwiri, P. Luthert, Richard Bowman, Mark E. Wood |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Community-based rehabilitation Retinal Neoplasms Tanzania Disease-Free Survival East africa Humans Medicine biology business.industry Retinoblastoma Incidence Incidence (epidemiology) Retrospective cohort study Hematology biology.organism_classification medicine.disease Standard error Oncology Child Preschool Pediatrics Perinatology and Child Health Female Pediatric ophthalmology business |
| Zdroj: | Pediatric Blood & Cancer. 50:160-162 |
| ISSN: | 1545-5017 1545-5009 |
| Popis: | We estimated the proportion of patients reaching a pediatric ophthalmology unit (Comprehensive Community Based Rehabilitation for Tanzania Disability Hospital, CCBRT) or an oncology unit (ORCI) in east Africa and investigated presentation, histology, and treatment outcomes of patients with retinoblastoma. A 5-year retrospective study identified 91 patients, representing approximately 18% of the nationwide total. Mean lag time was 10 months (standard deviation (SD) = 17) and mean follow-up was 8 months (SD = 11, range 0-40, n = 91). Thirty months disease-free survival probability was 0.23 (standard error = 0.07). Outcomes for retinoblastoma in Africa remain poor. The data presented here suggest strategies for improving the outcomes, including encouraging earlier presentation and establishment of multi-disciplinary treatment centers. |
| Databáze: | OpenAIRE |
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