Dynamic oxygenator blood volume during prolonged extracorporeal life support
| Autor: | Rik H. J. Hendrix, Eva R. Kurniawati, Sanne F. C. Schins, Jos G. Maessen, Patrick W. Weerwind |
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| Přispěvatelé: | MUMC+: MA Cardiothoracale Chirurgie (3), CTC, RS: Carim - V04 Surgical intervention, MUMC+: MA Extra Corp Circ CTC (5), MUMC+: MA Extra Corp Circ CTC (9) |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Adult
Extracorporeal Membrane Oxygenation/methods Male Monitoring Physiology Fluid Mechanics Oxygenators DEPOSITS Continuum Mechanics Biochemistry Physiologic/methods Carbon Dioxide/blood Extracorporeal Membrane Oxygenation Oxygen/blood Blood Flow Medicine and Health Sciences Humans Oxygenators/statistics & numerical data Hemoglobin Fluid Flow Flow Rate Monitoring Physiologic Pharmacology Multidisciplinary Blood Volume HEMOLYSIS Heparin Physics Biology and Life Sciences Classical Mechanics Proteins Drugs Fluid Dynamics Carbon Dioxide Middle Aged Body Fluids Oxygen Chemistry Blood Regional Blood Flow Physical Sciences Monitoring Physiologic/methods Female Anatomy INSENSIBLE WATER-LOSS Research Article Chemical Elements |
| Zdroj: | PLOS ONE, 17(2):e0263360. Public Library of Science PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Current methods for identification of oxygenator clotting during prolonged extracorporeal life support include visual inspection, evaluation of oxygenator resistance and oxygen exchange performance, and assessment of clotting-related laboratory parameters. However, these observations do not provide a quantitative assessment of oxygenator clot formation. By measuring changes in the dynamic oxygenator blood volume this study aimed to evaluate the relation to oxygenator resistance and oxygen transfer performance. Sixty-seven oxygenators were studied during adult extracorporeal life support. Oxygenator blood volume, oxygenator resistance, and oxygen transfer efficiency were monitored. Oxygenator blood volume decreased with increasing runtime (r = -0.462; p 2 transfer was found. Oxygenator blood volume declined over time and was clearly associated with an increasing oxygenator resistance during prolonged extracorporeal life support, though O2 transfer was less affected. |
| Databáze: | OpenAIRE |
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