Homoisoflavonoids and xanthones from the tubers of wild and in vitro regenerated Ledebouria graminifolia and cytotoxic activities of some of the homoisoflavonoids
| Autor: | Deborah D Shushu, Joan Mutanyatta, Bhagali G Matapa, Berhanu M. Abegaz |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Stereochemistry
Xanthones Flavonoid Anthraquinones Antineoplastic Agents Plant Science Horticulture Biology Biochemistry Plant Roots chemistry.chemical_compound Tissue culture Culture Techniques Xanthone Liliaceae Tumor Cells Cultured Ledebouria Humans Molecular Biology Nuclear Magnetic Resonance Biomolecular chemistry.chemical_classification Plants Medicinal Bicyclic molecule General Medicine biology.organism_classification Isoflavones In vitro Bulb chemistry Xanthenes |
| Zdroj: | Phytochemistry. 62(5) |
| ISSN: | 0031-9422 |
| Popis: | Eleven homoisoflavonoids and two xanthones were isolated and characterized from the bulbs of Ledebouria graminifolia. Five of the homoisoflavonoids are new compounds and were identified as: 5-hydroxy-7-methoxy-3-(4'-hydroxybenzyl)-4-chromanone, 5-hydroxy-6,7-dimethoxy-3-(4'-hydroxybenzyl)-4-chromanone, 5,7,8-trimethoxy-3-(4'-hydroxybenzyl)-4-chromanone, 5-hydroxy-3',4',7-trimethoxyspiro[2H-1-benzopyran-7'-bicyclo[4.2.0]octa-trien]-4-one, 5,7-dihydroxy-3',4'-dimethoxyspiro[2H-1-benzopyran-7'-bicyclo[4.2.0]octa-trien]-4-one. Structures were elucidated by extensive 1D, and 2D NMR spectroscopy and HRMS. A method for tissue culture was developed and the bulbs of mature plants were found to contain all the compounds isolated from the wild specimens of L. graminifolia. |
| Databáze: | OpenAIRE |
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