Acute and recurrent pancreatitis in children: etiological factors
| Autor: | Alfredo Larrosa-Haro, Rocío Macías-Rosales, José Sánchez-Corona, Silvia Esperanza Flores-Martínez, Carmen A. Sánchez-Ramírez, Alejandra Villa-Gomez |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Abdominal pain medicine.medical_specialty Pancreatic disease Adolescent Ileus Cystic Fibrosis Transmembrane Conductance Regulator Recurrent pancreatitis Recurrence Risk Factors Internal medicine Outcome Assessment Health Care medicine Humans Child Pancreas divisum business.industry General Medicine medicine.disease Surgery Hospitalization Cross-Sectional Studies Pancreatitis Abdominal trauma Child Preschool Mutation Pediatrics Perinatology and Child Health Acute pancreatitis Female medicine.symptom business |
| Zdroj: | Acta Paediatrica. 96:534-537 |
| ISSN: | 1651-2227 0803-5253 |
| DOI: | 10.1111/j.1651-2227.2007.00225.x |
| Popis: | Objectives To describe the clinical picture and outcome, and to assess the etiological factors of acute and recurrent pancreatitis in children. Methods Thirty-six (65.5%) patients with acute and 19 (34.5%) with recurrent pancreatitis were studied. Mean age was 126 (41.3 SD) months; 27 (49.1%) were females. Setting A pediatric referral hospital. Period 2000-2005. Design Cross-sectional. Variables Clinical and laboratory data and etiological factors. Statistics Chi2-test, Fisher test, OR, confidence interval, Student t-test and Mann-Whitney U-test. Results The most frequent symptom in acute and recurrent pancreatitis was abdominal pain, followed by vomiting and ileus. The severity of pancreatitis and complications were similar in both groups. Biliary stones, family history of pancreatitis, drug ingestion and hypercalcemia occurred in both groups. Abdominal trauma and acute hepatitis A occurred in patients with acute pancreatitis; triglyceride>5.65 mmol/L, pancreas divisum and DeltaF508 mutation occurred in patients with recurrent pancreatitis. No difference was observed when frequency factors between study groups were compared. Conclusions The clinical picture and etiological factors were similar in both groups. Since one out of every three children with acute pancreatitis in this series presented recurrences, it was not considered to be a 'benign disease'. Fifteen different etiological factors were identified in two-thirds of the cases. |
| Databáze: | OpenAIRE |
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