Nonrespiratory Complications and Obesity in Patients Dying with COVID-19 in Italy
| Autor: | Onder, Graziano, Palmieri, Luigi, Vanacore, Nicola, Giuliano, Marina, Brusaferro, Silvio, Agazio, Elvira, Andrianou, Xanthi, Barbariol, Pierfrancesco, Bella, Antonino, Bellino, Stefania, Benelli, Eva, Bertinato, Luigi, Boros, Stefano, Brambilla, Gianfranco, Calcagnini, Giovanni, Canevelli, Marco, Castrucci, Maria Rita, Censi, Federica, Ciervo, Alessandra, Colaizzo, Elisa, DAncona, Fortunato, Del Manso, Martina, Donfrancesco, Chiara, Fabiani, Massimo, Facchiano, Francesco, Filia, Antonietta, Floridia, Marco, Galati, Fabio, Grisetti, Tiziana, Kodra, Yllka, Langer, Martin, Lega, Ilaria, Lo Noce, Cinzia, Maiozzi, Pietro, Malchiodi Albedi, Fiorella, Manno, Valerio, Martini, Margherita, Mateo Urdiales, Alberto, Mattei, Eugenio, Meduri, Claudia, Meli, Paola, Minelli, Giada, Nebuloni, Manuela, Nisticò, Lorenza, Nonis, Marino, Palmisano, Lucia, Petrosillo, Nicola, Pezzotti, Patrizio, Pricci, Flavia, Punzo, Ornella, Puro, Vincenzo, Raparelli, Valeria, Rezza, Giovanni, Riccardo, Flavia, Cristina Rota, Maria, Salerno, Paolo, Serra, Debora, Siddu, Andrea, Stefanelli, Paola, Tamburo De Bella, Manuela, Tiple, Dorina, Unim, Brigid, Vaianella, Luana, Vichi, Monica, Rocco Villani, Emanuele, Zona, Amerigo |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Demographics Coronavirus disease 2019 (COVID-19) Endocrinology Diabetes and Metabolism Aged Aged 80 and over COVID-19 Comorbidity Female Humans Italy Middle Aged Obesity Odds Ratio Risk Factors SARS-CoV-2 Medicine (miscellaneous) 030209 endocrinology & metabolism Disease Logistic regression NO 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine death 80 and over medicine In patient 030212 general & internal medicine Nutrition and Dietetics business.industry obesity coronavirus disease Odds ratio medicine.disease Shock (circulatory) medicine.symptom business |
| Zdroj: | Obesity |
| ISSN: | 1930-739X |
| Popis: | OBJECTIVE: This study aimed to assess the impact of obesity on nonrespiratory complications in patients dying with coronavirus disease (COVID-19). METHODS: Medical charts of 3,694 of patients dying with COVID-19 in Italy were reviewed to extract information on demographics, preexisting comorbidities, and in-hospital complications leading to death. Multivariate logistic regressions were performed to assess the association of obesity with nonrespiratory complications. These analyses were adjusted for age, gender, and number of preexisting comorbidities. RESULTS: Obesity was present in 411/3,694 (11.1%) patients dying with COVID-19. Obesity was significantly associated with increased probability of experiencing acute renal failure (adjusted odds ratio [OR], 1.33; 95% CI: 1.04-1.71) and shock (adjusted OR, 1.54; 95% CI: 1.19-1.99). The associations of obesity with acute renal failure and shock were stronger in patients aged < 60 years (adjusted OR, 2.00; 95% CI: 1.09-3.67 and OR, 2.37; 95% CI 1.29-4.36) than in those aged 60 years or older (adjusted OR, 1.20; 95% CI: 0.90-1.60 and OR, 1.22; 95% CI: 0.91-1.65). CONCLUSIONS: In patients dying with COVID-19 in Italy, obesity is associated with an increased probability of nonrespiratory complications, particularly shock and acute renal failure. These associations seem stronger in younger than in older adults. Strategies should be put in place in patients with COVID-19 with obesity to prevent these complications. |
| Databáze: | OpenAIRE |
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