Combination Therapy with Ibuprofen and Methadone for Chronic Cancer Pain
| Autor: | Patricia A. Ganz, Theresa Ferrer-Brechner |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male Combination therapy Narcotic medicine.medical_treatment Emotions Ibuprofen Euphoriant law.invention Random Allocation Pharmacotherapy Double-Blind Method Randomized controlled trial law Neoplasms medicine Humans Aged Clinical Trials as Topic business.industry General Medicine Middle Aged Crossover study Pain Intractable Anesthesia Drug Therapy Combination Female business Methadone medicine.drug |
| Zdroj: | The American Journal of Medicine. 77:78-83 |
| ISSN: | 0002-9343 |
| DOI: | 10.1016/s0002-9343(84)80023-6 |
| Popis: | This randomized double-blind crossover study compares the narcotic methadone alone with methadone in combination with the peripherally acting, antiprostaglandin agent ibuprofen (Motrin, Upjohn) in 28 patients with moderate to severe cancer-related pain, who were already using a narcotic for pain relief. Results show that the addition of 600 mg of ibuprofen to either 2.5 or 5 mg of methadone significantly increased analgesia, without concomitantly increasing side effects or euphoria. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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