Extracorporeal Membrane Oxygenation in Cardiogenic Shock due to Acute Myocardial Infarction: A Systematic Review
Autor: | Alina-Elena Nedelcu, Adrian Covic, Catalina Arsenescu Georgescu, Simona Daniela Zavalichi, Cristian Stătescu, Marius Andrei Zavalichi, Ionut Nistor |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Gastrointestinal bleeding Article Subject medicine.medical_treatment Myocardial Infarction Shock Cardiogenic 030204 cardiovascular system & hematology Disease-Free Survival General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Extracorporeal Membrane Oxygenation 0302 clinical medicine Reperfusion therapy Extracorporeal membrane oxygenation Humans Medicine 030212 general & internal medicine Myocardial infarction Survival rate General Immunology and Microbiology business.industry Cardiogenic shock General Medicine medicine.disease Survival Rate surgical procedures operative Shock (circulatory) Emergency medicine Myocardial infarction complications medicine.symptom business Research Article |
Zdroj: | BioMed Research International BioMed Research International, Vol 2020 (2020) |
ISSN: | 2314-6141 2314-6133 |
Popis: | Background. Cardiogenic shock is associated with high mortality, despite new strategies for reperfusion therapy. Short-term circulatory support devices may provide adequate support for appropriate myocardial and organ perfusion. Objectives. This review is aimed at evaluating the impact on survival when using venoarterial extracorporeal membrane oxygenation (V-A ECMO) in patients with cardiogenic shock due to acute myocardial infarction (AMI). Methods. We performed a systematic review that included studies using V-A ECMO in patients with cardiogenic shock. Time on ECMO, side effects, and the number of deceased patients, transplanted or upgraded to durable assist devices were analysed. Literature search was done using PubMed/MEDLINE (inception (1969) to January 10, 2019), ProQuest (inception (January 14, 1988) to January 10, 2019), and clinicaltrials.gov (inception (September 12, 2005) to January 10, 2019), by 2 authors. This protocol is registered with PROSPERO (no. CRD42019123982). Results. We included 9 studies with a total of 1,998 adult patients receiving V-A ECMO for AMI-induced cardiogenic shock. Survival rate varied from 30.0% to 79.2% at discharge and from 23.2% to 36.1% at 12 months. Time on ECMO varied between 1.96 and 6.0 days. Reported serious adverse events were gastrointestinal bleeding (3.6%) and peripheral complications (8.5%). Conclusion. The use of V-A ECMO among patients with AMI-induced cardiogenic shock may provide survival benefits. However, V-A ECMO treatment effects are inconclusive because of limitations in cohort design and reporting. |
Databáze: | OpenAIRE |
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