| Autor: |
Misako Higashida-Konishi, Mitsuhiro Akiyama, Tatsuya Shimada, Satoshi Hama, Tatsuhiro Oshige, Keisuke Izumi, Hisaji Oshima, Yutaka Okano |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Rheumatology International. 43:545-549 |
| ISSN: |
1437-160X |
| DOI: |
10.1007/s00296-022-05217-x |
| Popis: |
Glucocorticoid remains the mainstay for treatment of large vessel vasculitis (LVV) including giant cell arteritis (GCA); however, the disease affects the elderly for whom the adverse effects of glucocorticoid are problematic. Recently, some reports have suggested that intravenous tocilizumab (TCZ) monotherapy is effective for this disease. To date, it remains unknown whether subcutaneous TCZ monotherapy is also effective. Here, we present a first case of GCA successfully treated with subcutaneous TCZ monotherapy. A 75-year-old woman presented with shoulder and hip pain. She was diagnosed with polymyalgia rheumatica (PMR) and treated with low-dose prednisolone (15 mg daily); however, she discontinued glucocorticoid therapy at her discretion due to the psychiatric adverse effect (cognitive dysfunction). Seven months later, her shoulder and hip pain relapsed. Furthermore |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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