Intravenous thrombolytic therapy in acute ischemic stroke: Experiences of Adıyaman

Autor: Ali Zeynal Abidin Tak, Ali Arik, Yaşar Altun, Erman Altunisik
Rok vydání: 2020
Předmět:
Zdroj: Türk Beyin Damar Hastalıkları Dergisi, Vol 26, Iss 3, Pp 262-268 (2020)
ISSN: 2146-9113
1301-1375
DOI: 10.5505/tbdhd.2020.85547
Popis: INTRODUCTION[|]Stroke, which poses a huge burden on the health economy all over the world and has negative effects on caregivers, is a serious cause of disability and mortality. The aim of our study was to share the results of intravenous (IV) thrombolytic therapy (tPA) applied to patients with acute ischemic stroke in our neurology clinic in Adıyaman province.[¤]METHODS[|]Between March 2018 and June 2020, the time of admission to our clinic with the diagnosis of acute ischemic stroke (within the first 4.5 hours) and the application of thrombolytic therapy in our clinic and the responses to treatment of 44 patients who were clinically eligible for IV tPA were analyzed retrospectively. Clinical data and demographic characteristics of the patients were recorded.[¤]RESULTS[|]A total of 44 patients with acute ischemic stroke, 24 female (54.5%) and 20 male (45.5%) were included in the study. The mean age of the patients was 69.84 +- 12.82 (range, 38-96) years. Intracranial bleeding was observed in 3 patients (6.8%) after treatment. Symptomatic bleeding was detected in only 1 (2.3%) of them. The mean NIHHS and mRS scores of the patients with anterior circulation infarction were 2.78 and 1.09, respectively, at the 3rd month follow-up after treatment, and the mean NIHSS and mRS scores at the 3rd month controls of those with posterior circulation infarction were 3.33 and 1.00, respectively. Three patients with anterior circulation infarction died within 1 week after treatment.[¤]DISCUSSION AND CONCLUSION[|]In recent years, the number of applications for acute ischemic stroke to our stroke center has been increasing day by day. For patients presenting with acute ischemic stroke, iv tPA therapy is the only treatment option with proven efficacy under appropriate conditions and at the appropriate time.[¤]
Databáze: OpenAIRE
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