Pythium insidiosum: A Rare Necrotizing Orbital and Facial Infection
| Autor: | Sandra R. Arnold, Maria Kirzhner, Cari E. Lyle, Leonel L. Mendoza, James C. Fleming |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Ischemia Pythium Eye Pythium insidiosum Microbiology Diagnosis Differential Necrosis Eosinophilic Orbital Diseases medicine Humans Swamp cancer Pythiosis Child Tropism Vaccines biology General Medicine medicine.disease biology.organism_classification Thrombosis Infectious Diseases Face Pediatrics Perinatology and Child Health Female Orbital cellulitis |
| Zdroj: | Journal of the Pediatric Infectious Diseases Society. 4:e10-e13 |
| ISSN: | 2048-7207 2048-7193 |
| DOI: | 10.1093/jpids/piu015 |
| Popis: | Pythium insidiosum, also known as "swamp cancer," has been long known for its destructive effects on plants and animals. Infections with this fungus-like organism typically occur in temperate, tropical, and subtropical regions [ 1]. Human infection with P insidiosum, although exceedingly rare, is characterized by invasion of the cornea, cutaneous, subcutaneous, and orbital tissues with eosinophilic, tumor-like masses demonstrating arterial tropism [ 1, 2]. In most cases, patients have a history of recent exposure to wet environments [ 1]. If left untreated, P insidiosum is fatal, because it is an angioinvasive organism that leads to thrombosis and tissue ischemia. Reports of most human cases are from Thailand, with only 4 well documented orbital cases to date in the United States and Australia [ 1, 3, 4]. |
| Databáze: | OpenAIRE |
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