Indocyanine green clearance as an outcome prediction tool in cardiac surgery: A prospective study
| Autor: | Christian Hinske, Lahib Adnan, Felix Kur, Andres Beiras-Fernandez, Patrick Möhnle, Florian Weis, Calin Vicol, Erich Kilger, K Nassau |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Indocyanine Green Male Cardiac function curve medicine.medical_specialty Time Factors Multivariate analysis Critical Care and Intensive Care Medicine law.invention chemistry.chemical_compound law medicine Humans Postoperative Period Prospective Studies Cardiac Surgical Procedures Coronary Artery Bypass Coloring Agents Prospective cohort study Aged Aged 80 and over business.industry Coronary Care Units Age Factors EuroSCORE Perioperative Length of Stay Middle Aged Prognosis Heart Valves Intensive care unit eye diseases Cardiac surgery Surgery chemistry Female business Indocyanine green |
| Zdroj: | Journal of Critical Care. 29:224-229 |
| ISSN: | 0883-9441 |
| Popis: | Purpose To evaluate the role of plasma disappearance rate of indocyanine green (PDR-ICG) as an outcome prediction tool in cardiac surgery. Patients and Methods One hundred ninety patients undergoing coronary artery bypass grafting, valve surgery or combined procedures were enrolled. PDR-ICG measurements along with standard lab values were performed preoperative and on postoperative days 1, 2, and on discharge from the intensive care unit. Adverse outcomes were defined as prolonged length of stay in the intensive care unit and/or mortality. Two groups were defined according to length of stay in the intensive care unit (≤ 3 days vs > 3 days). Results PDR-ICG values differed significantly for all time points between the groups. In a multivariate model, in patients over 65 years with a EuroSCORE below 8.5, a preoperative PDR-ICG value below 12.85%/min was the strongest independent predictor for prolonged intensive care unit stay (> 3 days). A preoperative PDR-ICG value below 8.2%/min was the strongest independent predictor for mortality in a multivariate analysis including age, cardiac function, and EuroSCORE. Conclusions In addition to the established scores, PDR-ICG may provide valuable information for the assessment of perioperative morbidity and mortality in cardiac surgery. Pre- and early postoperative measurements may help to identify patients at risk for developing perioperative complications. |
| Databáze: | OpenAIRE |
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