Electrosynthesis of nano-sized pyran and chromene derivatives by one-pot reaction between cyclic-1,3-diketons, malononitrile/ethyl cyanoacetate, and isatins
| Autor: | Behrooz Mirza, Mohsen Zeeb, Mohaddeseh Taheri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Cyclic-1
010405 organic chemistry Potassium bromide Nanochemistry Nanoparticle Electrolyte 010402 general chemistry Electrosynthesis 01 natural sciences Combinatorial chemistry 0104 chemical sciences 3-diketones lcsh:Chemistry chemistry.chemical_compound Cyclohexane-1 3-dione chemistry lcsh:QD1-999 Pyran Ethyl cyanoacetate Electrocatalytic three-component synthesis 1H-indene-1 3(2H)-dione Malononitrile |
| Zdroj: | Journal of Nanostructure in Chemistry, Vol 8, Iss 4, Pp 421-429 (2018) |
| ISSN: | 2193-8865 2008-9244 |
| Popis: | An efficient and sustainable method was developed for the electrocatalytic synthesis of nano-sized 4H-pyran derivatives via a green, one-pot, three-component condensations of cyclic-1,3-diketones [including 1H-indene-1,3(2H)-dione, cyclohexane-1,3-dione, cyclopentane-1,3-dione, pyrimidine-2,4,6(1H,3H,5H)-trione], malononitrile or ethyl cyanoacetate, and isatins in an undivided electrochemically cell applying potassium bromide as the electrolyte in the alcoholic media. This electrosynthesis was introduced as a reliable and cost-effective approach for the high-yielding synthesis (76–92%) of the target compounds. The synthesized 4H-pyran and chromene nanoparticles could open an effective way for production of nano-sized drugs. Graphical abstract |
| Databáze: | OpenAIRE |
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