Tetrahydrocannabinols and serum prolactin levels in man
| Autor: | James Clemens, Ross E. Crabtree, Howard Rowe, Louis Lemberger |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Tachycardia
medicine.medical_specialty Centrally acting drugs Time Factors Prolactin blood Placebo General Biochemistry Genetics and Molecular Biology Serum prolactin Placebos Heart Rate Internal medicine mental disorders medicine Humans Psychology Dronabinol General Pharmacology Toxicology and Pharmaceutics Cannabis Clinical Trials as Topic business.industry organic chemicals Smoking General Medicine Crossover study Prolactin Endocrinology medicine.symptom business Symptom score |
| Zdroj: | Life sciences. 16(8) |
| ISSN: | 0024-3205 |
| Popis: | δ 9 -THC, 11-OH-δ 9 -THC or placebo was administered to casual marihuana smokers in a double-blind, crossover study. δ 9 -THC and 11-OH-δ 9 -THC produced marked pharmacologic and psychologic effects (tachycardia, increased symptom score and psychologic high). In contrast to effects produced by many other centrally acting drugs, the acute administration of these cannabinoids was devoid of any significant effect on prolactin secretion as determined by monitoring changes in serum prolactin levels. |
| Databáze: | OpenAIRE |
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