Monoclonal gammopathy among patients with chronic hepatitis C infection

Autor: Iqbal Siddique, David Nkansa-Dwamena, Fuad Hassan, Hisham Abu El-Naga, Salem H. Alshemmari, Reem Ameen
Rok vydání: 2002
Předmět:
Zdroj: Medical principles and practice : international journal of the Kuwait University, Health Science Centre. 13(2)
ISSN: 1011-7571
Popis: Objective: To determine the prevalence of monoclonal gammopathies in Kuwait and its association with chronic hepatitis C virus (HCV) infection. Methodology: Serum protein electrophoresis and measurement of immunoglobulin levels were carried out prospectively in 100 consecutive patients with chronic HCV infection. Results: Among the 100 patients tested (82 males, 18 females; median age 45 years), 59 had polyclonal band in serum protein electrophoresis while the other 41 had a normal pattern. None of the patients had monoclonal gammopathy. The mean serum immunoglobulin levels were: IgG 18.4 g/l (range 4–39), IgA 2.9 g/l (range 0.09–8) and IgM 1.6 g/l (range 0.14–6.08). Conclusion: There was no evidence of monoclonal gammopathies in patients with chronic HCV infection in Kuwait.
Databáze: OpenAIRE